أضخم موقع علمي صحي موثق في العالم لسعادة العائلة وصحتها, بالعلم والإيمان نبني الميزان

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The role of nutrition related genes and nutrigenetics in understanding the pathogenesis of cancer

The role of nutrition related genes and nutrigenetics in understanding the pathogenesis of cancer



 

         
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  5 Abstract
 
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The etiology and pathogenesis of cancer is a complex interplay mechanism of genetic and environmental factors. Dietary intake and nutrient supplements are considered essential environmental factors, so scientists have reported that dietary and nutrients could play an important role in cancer development. Moreover, many studies have reported the intimate link of the quantity and quality of dietary nutrients with cancer incidence and pathogenesis.

There is a marked variation in cancer development with the same dietary intake between individuals. This could be explained by the variation in their genetic polymorphisms, which leads to the emerge of the concept of nutrigenomics and nutrigenetics. Nutrigenomics and nutrigenetics may explain the association of specific nutrient intake with genetic variations on cancer pathogenesis. Nowadays, nutrigenomics is widely used for discussing cancer development and pathogenesis or even the response to treatment as well as diet-related or dependent diseases. Subsequently, nutrigenomics may proceed in respect of the effective management of cancer in an individualized nutritional consultation according to the individuals’ genetic profiles.

 
  7 Article Published Date 2016  
  12 Link

 

https://www.sciencedirect.com/science/article/pii/S2213879X16000183#sec0100

 

 
         

 


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